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Statistics & data analysis

Systematic review help, from protocol to PRISMA flow diagram

A systematic or scoping review lives or dies on its method. We help you plan a transparent protocol, build reproducible searches and handle screening, appraisal and synthesis so that the review holds up to examiners and peer reviewers.

Systematic, scoping or something else?

Choosing the review type early saves weeks. A systematic review answers a focused question, appraises study quality and synthesises findings, sometimes statistically. A scoping review maps the extent and nature of evidence on a broader topic, usually without formal quality appraisal, and follows JBI guidance and PRISMA-ScR. Rapid reviews streamline some steps for time-sensitive questions, and umbrella reviews synthesise existing reviews.

If your aim is to build an argument from selected sources rather than exhaustively collect evidence, a narrative review may serve better, and our literature review help is the more natural fit.

The review stages we support

StageWhat we help with
Question and protocolFramework choice, eligibility criteria, outcomes and a registration-ready protocol
SearchingSubject headings (MeSH, Emtree) combined with free-text terms, Boolean logic, truncation and proximity operators, grey literature
ScreeningPilot screening, calibration between reviewers, recording reasons for full-text exclusion
Extraction and appraisalExtraction forms, plus tools such as RoB 2, ROBINS-I, CASP, JBI checklists or the Newcastle-Ottawa Scale
SynthesisMeta-analysis, narrative synthesis following SWiM guidance, or charting for scoping reviews; GRADE for certainty of evidence
ReportingPRISMA 2020 checklist and flow diagram, tables of included studies

Where reviews usually go wrong

The most common weakness is a search that cannot be reproduced: one database, no subject headings, no record of the date or the exact string. Close behind are eligibility criteria written so loosely that two reviewers disagree on half the abstracts, and meta-analyses that pool studies too different to combine. We also see PRISMA diagrams where the numbers do not add up, and risk-of-bias judgements that never feed into the conclusions.

When pooling is appropriate, we explain the choice between fixed- and random-effects models and how to read I² and tau² so you can describe heterogeneity accurately. For the underlying statistics, our guide to hypothesis testing and p-values is a useful refresher.

A worked example shows how much structure matters. Suppose your question is whether exercise programmes reduce depressive symptoms in older adults. Using PICO, the population is adults aged 65 and over, the intervention is structured exercise, the comparison is usual care or no exercise, and the outcome is a validated depression score. Each element becomes a block of synonyms and subject headings joined by OR, and the blocks are joined by AND. Writing that out before you search makes the eligibility criteria almost write themselves, and it gives a second screener a clear basis for decisions.

Getting started

Send your draft question, any protocol or proposal, the databases you can access through your library, and your deadline. If you have already searched, include the exported strings and record counts. A protocol and search strategy review usually takes three to five working days; ongoing support through screening and synthesis is planned around your timeline. Request a free quote and we will reply within a few hours.

If you are part of a team, tell us who will screen and extract, so we can suggest a calibration exercise and a simple way to resolve disagreements before the main screening starts.

Rigour you can document

Systematic reviews are judged on transparency: could someone else repeat what you did and reach the same set of studies? Our support is designed to leave a clear audit trail of decisions, so you can explain them in your methods section or viva. You remain the reviewer and author, and we follow the boundaries set out on our academic integrity page. If your review feeds into a paper, our publication support can help with journal selection and submission.

What you get

  • Feedback on your review question framed with PICO, PEO, SPIDER or PCC
  • A protocol review aligned with PRISMA-P, ready for PROSPERO or OSF registration
  • Database-specific search strings for sources such as MEDLINE, Embase, CINAHL, PsycINFO, Scopus and Web of Science
  • Screening and data extraction templates, with set-up help in Covidence, Rayyan or a spreadsheet
  • Guidance on risk-of-bias tools and, where suitable, meta-analysis with forest plots and heterogeneity statistics
  • A PRISMA 2020 or PRISMA-ScR checklist and flow diagram check before submission

What we don't do

  • Acting as the independent second screener on an assessed student review unless your programme permits it; instead we show you how to document screening decisions properly
  • Guaranteeing acceptance by a journal or registration body
  • Writing your discussion or conclusions; we help you interpret the evidence so you can write them

Our integrity policy

How it works

  1. Describe your project

    Level, deadline and what you need help with.

  2. Agree a written scope

    What's included, the price and the timeline.

  3. Work in stages

    Check-ins so you can steer the work.

  4. Review and ask

    Explanations and follow-up questions included.

Frequently asked questions

What is the difference between a systematic review and a scoping review?
A systematic review answers a focused question and appraises the quality of included studies. A scoping review maps the breadth of evidence on a broader topic and usually does not assess risk of bias.
Do I need to register my protocol?
For systematic reviews in health and social care, registering on PROSPERO is strongly encouraged and often expected by journals. Scoping reviews cannot be registered on PROSPERO but can be registered on OSF or published as a protocol.
Can you build my search strategy?
We help you develop and test it, translating it across databases with the correct subject headings and syntax, and explain each part so you can report and update it yourself.
Can you run a meta-analysis?
Yes, where the included studies are similar enough to pool. We work in R (metafor, meta), Stata or RevMan and explain effect sizes, heterogeneity and sensitivity analyses.
How many reviewers does a systematic review need?
Best practice is at least two independent reviewers for screening and extraction. If you are a student working alone, check your programme's rules and we can advise on documenting a defensible alternative.
How long does a full systematic review take?
Usually several months from protocol to final report, depending on the number of records. Plan the timeline early, because screening thousands of abstracts takes longer than most people expect.

Ready when you are

Share a few details about your project and get a written quote, with no obligation.

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